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Pairing cells of different sizes in a microfluidic device for immunological synapse monitoring

Faruk Azam Shaik, Clara Lewuillon, Aurélie Guillemette, Bahram Ahmadian, Carine Brinster, Bruno Quesnel, Dominique Collard, Yasmine Touil, Loïc Lemonnier, Mehmet Tarhan

Analyzing cell–cell interaction is essential to investigate how immune cells function. Elegant designs have been demonstrated to study lymphocytes and their interaction partners. However, these devices have been targeting cells of similar dimensions. T lymphocytes are smaller, more deformable, and…

Lab on a Chip, 2022, 22 (5), pp.908-920. ⟨10.1039/d1lc01156a⟩. ⟨hal-03565627⟩